AICAR 50mg

An analogue of AMP that switches on AMPK, the enzyme cells use to sense when energy is low. Activating it mimics the state of a muscle mid-workout: glucose uptake rises, fat is burned for fuel and cells build more mitochondria. It became famous when sedentary mice given AICAR ran about 44% farther than untreated mice without any training, which earned it the label "exercise in a pill". It is studied for endurance, metabolic disease, insulin sensitivity and protecting tissue during reduced blood flow, and is one of the reference compounds in exercise-mimetic research.